A broad spectrum control. Active ingredient is Azadirachtin, made from seeds of Neem trees. Bioneem interrupts insects' growth cycle causing death. Controls 30 common pests including grasshoppers, whiteflies, mealybugs, caterpillars, aphids and webworms. Low toxicity rating. No known insect resistance since it was developed 12 years ago. Harmful to ladybugs. 16 oz.